1
زیست شناسی::
شبکه اندوپلاسمی
(B) The SRP attaches to a SRP receptor on the endoplasmic reticulum (ER) membrane.
(C) The secretory protein is translocated into the lumen of the ER, and a signal peptidase removes the signal sequence.
incorrect folding of the polypeptide, the activation of cellular mechanisms to cope with the stress of protein overproduction, and the aberrant process ing and release of the protein of interest from the endoplasmic reticulum.
Correct protein folding occurs in the endoplasmic reticulum in eukaryotes and is facilitated by a number of different proteins, including molecular chaperones, enzymes that promote disulfide bond formation, signal trans duction proteins that monitor the demand and capacity of the protein folding machinery, and proteases that clear away improperly folded or aggregated proteins (Fig. 3.29).
Figure 3.29 Summary of protein folding in the endoplasmic reticulum of yeast cells.
واژگان شبکه مترجمین ایران
2
عمومی::
رتیکولوم اندوپلاسمیک
Initiation of cellular signaling by the activation of the mGluR leads to the release of stored Ca2+ from the endoplasmic reticulum (ER) via
pyknosis of the nucleus, and swelling of the mitochondria and ER.
واژگان شبکه مترجمین ایران